The role:
As a Senior ADME Scientist you will support drug discovery projects by designing and running bioanalytical assays to determine the metabolic fate of novel small molecule pharmaceuticals.
Responsibilities:
- Carry out analytical assay development to solve specific and complex problems.
- Work collaboratively with biology and chemistry to progress drug discovery projects.
- Run a range of In vitro ADME assays (such as metabolic turnover assays and permeability assays)
- Carry out a range of bioanalysis including cell-based assays and LC-MS/MS.
- Write and present reports project teams.
Ideal candidates:
Will have a degree, Masters or PhD in Biochemistry or Chemistry (or related subject) and have experience working in ADME/ DMPK Bioanalysis. As a Senior ADME Scientist you will have experience in in-vitro ADME assays and bioanalysis including cell-based assays. Experience in mammalian cells, plate-based assays, protein analysis, metabolic turnover assays, permeability assays and mass spectroscopy (LC-MS/ QTOF) is highly desirable.
The company is rapidly growing and based within one of the leading scientific research and innovation hubs in the UK.
They offer a highly competitive salary and benefits package, and an opportunity to join a growing and rewarding company.
Please note the company is unable to sponsor visas for candidates without eligibility to work in the UK
Key words: Bioanalysis, Bioanalytical, DMPK, ADME, Cell-based Assays, LC-MS, QTOF, Biochemist, Mammalian, invitro, Purification, Protein, metabolic turnover, permeability
